The Brazil midfielder made way after 18 minutes of Wednesday’s match at Anfield and must now sit out a potentially pivotal period of the Reds’ campaign.
“Further assessment on the injury has discovered Fabinho will be out of action until the new year,” a club statement read.
“The Brazilian will begin a rehabilitation programme with the Reds’ medical team at Melwood as he works his way back to full fitness.”
Jurgen Klopp’s side will battle across four fronts over the next month, defending an eight-point lead at the Premier League summit.
A share of the spoils in midweek means they head to Salzburg on December 10 with qualification for the knockout stages of the Champions League still on the line.
A scratch squad will take on Aston Villa in the quarter-finals of the EFL Cup on December 17, a day before Liverpool begin their Club World Cup bid in Qatar.
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