Mane picked up the problem on international duty with Senegal and was withdrawn late on in Saturday’s 2-0 World Cup qualifying triumph over Cape Verde.
It will be Mane’s second lengthy spell out of the season, after picking up a three-match ban for a dangerous challenge on Manchester City goalkeeper Ederson in September.
The 25-year-old – who has three goals in five Premier League games – has only been involved in one domestic match since returning from that suspension, and now looks set for an even longer absence.
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