Neymar starred with his 52nd international goal as high-flying Brazil overcame Paraguay 3-0 on Tuesday but the CONMEBOL leaders still needed a favourable result in Peru.
And Tite’s men - amid a nine-game winning streak since last year’s Copa America Centenario - benefited from Peru’s 2-1 win at home to struggling Uruguay as the five-time world champions are assured of at least a fourth-place finish, officially stamping their ticket to Russia 2018.
Peru’s victory, while keeping their own qualification hopes alive, left third-placed Uruguay 10 points adrift.
With four rounds remaining, Brazil are 11 points clear of Argentina - who are fifth and occupy the play-off spot and will face Uruguay in August.
Brazil are back in qualifying action against Ecuador in the same month.
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